It is important to discuss the risks and benefits of treatment with your doctor and caregivers. For women who take antidepressant medications during weeks 13 through the end of their pregnancy second and third trimesters , there is a risk that the baby can be born before it is fully developed before 37 weeks.
This is a potentially fatal condition that is associated with use of the antidepressant in the second half of pregnancy.
However, women who discontinued antidepressant therapy were five times more likely to have a depression relapse than those who continued their antidepressant.
If you are pregnant, please discuss the risks and benefits of antidepressant use with your health care provider. Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks.
The dose usually ranges from 50 mg to mg. Only your health care provider can determine the correct dose for you. If you are taking it for PMDD, sertraline can be taken once daily everyday or intermittently usually starting 14 days prior to menstruation through the first full day of menses of each cycle. The liquid should be measured with an oral syringe or dropper which you can get from your pharmacy.
It should not be mixed in advance. Consider using a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or friend to remind you or check in with you to be sure you are taking your medication. If you miss a dose of sertraline, take it as soon as you remember, unless it is closer to the time of your next dose.
Discuss this with your health care provider. Do not double your next dose or take more than what is prescribed. Avoid drinking alcohol or using illegal drugs while you are taking antidepressant medications.
They may decrease the benefits e. If an overdose occurs, call your doctor or You may need urgent medical care. You may also contact the poison control center at Sexual side effects, such as problems with orgasm or ejaculatory delay often do not diminish over time. Low sodium blood levels symptoms of low sodium levels may include headache, weakness, difficulty concentrating and remembering , teeth grinding, angle closure glaucoma symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye.
Serotonin syndrome symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death , seizure. SSRI antidepressants including sertraline may increase the risk of bleeding events.
Combined use of aspirin, nonsteroidal anti-inflammatory drugs e. This may include gums that bleed more easily, nose bleed, or gastrointestinal bleeding. Some cases have been life threatening. To date, there are no known problems associated with long term use of sertraline. It is a safe and effective medication when used as directed. Sertraline should not be taken with or within two weeks of taking monoamine oxidase inhibitors MAOIs.
Sertraline may increase the effects of other medications that can cause bleeding e. Sleep, energy, or appetite may show some improvement within the first weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to weeks to fully improve.
Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Taking sertraline for more than a year has also been linked to a small increased risk of getting diabetes.
You'll be regularly checked for this. Sertraline is not any better or worse than other antidepressants. Sometimes people respond better to one antidepressant than another. Sertraline can make you feel more or less hungry than usual, so you may lose or gain weight when you start taking it.
If you start to have problems with your weight while taking sertraline, talk to your doctor or pharmacist. Sertraline will not affect any type of contraception, including the contraceptive pill or emergency contraception. There's some evidence that sertraline can reduce the quality of sperm.
This should reverse once you stop taking the medicine. It's not known whether this reduces male fertility. Talk to your doctor if you're concerned. There's no firm evidence to suggest that taking sertraline will reduce fertility in women. But speak to a pharmacist or your doctor if you're trying to get pregnant. They may want to review your treatment. The positive effects of sertraline may, after a while, improve your sex life as your mood lifts and you become interested in life and relationships again.
Sexual side effects usually pass after the first couple of weeks. However, very rarely, they can be long lasting and may not get better even after stopping the medicine. If these happen and are a problem for you, go back to your doctor to see if there's another treatment you can try. Some people cannot concentrate properly while they're taking sertraline.
It might be best to stop driving and cycling for the first few days of treatment until you know how this medicine makes you feel. You can drink alcohol while taking sertraline, but it may make you feel sleepy. It might be best to stop drinking alcohol until you see how the medicine makes you feel. Grapefruit juice can increase the amount of sertraline in your body and increase the risk of side effects. Antidepressants, including sertraline, are just one of several approaches to treating depression.
Cannabis with sertraline can give you a fast heartbeat. Cannabis can also make drowsiness worse with sertraline, especially in people who have just started taking it. Methadone can increase the risk of side effects in people taking sertraline. Talk to your doctor if you think you might use recreational drugs while taking sertraline.
Page last reviewed: 12 December Next review due: 12 December Sertraline - Brand name: Lustral On this page About sertraline Key facts Who can and cannot take sertraline How and when to take it Side effects Pregnancy and breastfeeding Cautions with other medicines Common questions about sertraline. About sertraline Sertraline is a type of antidepressant known as a selective serotonin reuptake inhibitor SSRI.
Sertraline comes as tablets, which are available only on prescription. Help us improve our website Can you answer a quick question about your visit today? It usually takes 4 to 6 weeks for sertraline to work.
Side effects such as feeling sick, headaches and trouble sleeping are common. They're usually mild and go away after a couple of weeks. If you and your doctor decide to take you off sertraline, your doctor will probably recommend reducing your dose gradually to help prevent extra side effects.
Check with your doctor before starting sertraline if you: have had an allergic reaction to sertraline or any other medicines in the past have a heart problem — sertraline can speed up or change your heartbeat have ever taken any other medicines for depression — some rarely used antidepressants can interfere with sertraline to cause very high blood pressure, even when they have been stopped for a few weeks are trying to become pregnant, already pregnant or breastfeeding have an eye problem called glaucoma — sertraline can increase the pressure in your eye have epilepsy or are having electroconvulsive treatment — sertraline may increase your risk of having a seizure If you have diabetes , sertraline can make it more difficult to keep your blood sugar stable.
Take sertraline once a day. You can take sertraline with or without food. If you have trouble sleeping, it's best to take it in the morning. Dosage The usual dose of sertraline is 50mg a day in adults. What if I forget to take it? What if I take too much? Urgent advice: Call your doctor straight away if:. You have taken too much sertraline and have symptoms such as: being sick vomiting shaking feeling sleepy dizziness fast heart rate fits or seizures.
Common side effects and self-help advice These common side effects happen in more than 1 in people. Feeling sick Try taking sertraline with or after food. Headaches Make sure you rest and drink plenty of fluids. Being unable to sleep Take sertraline first thing in the morning. Feeling sleepy Take sertraline in the evening and cut down the amount of alcohol you drink. Diarrhoea Drink plenty of water or other fluids to avoid dehydration. Dry mouth Chew sugar-free gum or sugar-free sweets.
Dizziness If sertraline makes you feel dizzy, stop what you're doing and sit or lie down until you feel better. Feeling tired or weak If sertraline makes you feel tired or weak, stop what you're doing and sit or lie down until you feel better. Serious side effects It happens rarely in less than 1 in people , but some people may have serious side effects when taking sertraline.
Information: You can report any suspected side effect using the Yellow Card safety scheme. Visit Yellow Card for further information. If you are currently breastfeeding or pregnant, or if you plan to become pregnant, discuss the risks and benefits of treatment with your physician. Like all medicines, Zoloft carries a risk for side effects. Common side effects such as headache, sleep difficulties, dry mouth, sweating, and loss of appetite are typically mild and may subside in a few days or weeks.
Let your doctor know right away if you experience more severe side effects such as chest pain, skin rash, vomiting, anxiety, diarrhea, aggression, or confusion. Although the syndrome is not generally considered dangerous, the symptoms can be distressing.
Don't lower your dose or suddenly stop taking Zoloft without your doctor's approval. Ever wonder what your personality type means? Sign up to find out more in our Healthy Mind newsletter. Food and Drug Administration. Chonnam Med J. Swanson J. Scientific American. December 10, Updated January 2, National Center for Complementary and Integrative Health. John's Wort and Depression: In Depth. Updated December Sertraline Drug Interactions.
Front Psychiatry. National Alliance on Mental Illness. Sertraline Zoloft. December Gabriel M, Sharma V. Antidepressant discontinuation syndrome. Hosenbocus S, Chahal R. Your Privacy Rights. To change or withdraw your consent choices for VerywellMind. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page.
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